Before 1962, the parish was part of Binondo until the late Cardinal Rufino Santos established within the La Loma Cemetery area a parish on October 11, 1962 with Msgr. Melencio de Vera as the pioneering pastor.  Followed by Fr. Armando S. Ligon, Fr. Vicente Coronel, Fr. Arsenio Nalunat and Fr. Ardie Ong, the newly installed parish priest.

The parish has a population of 57,230 — 89% are Catholics and the rest of different religious denominations. From 1963 to date, 14 traditional lay associations were formed to assist the parish priest.

In relation to the parish Mission-Vision Statement of bringing the Church closer to people – street masses are done regularly—home visitation, block rosary and Charismatic core group are actively participated in by parishioners.

The dynamic Fr. Ardie Ong is working on a plan to expand the Formation Center and build a mortuary parlor. The Parish Pastoral Council dreams of a school for marginalized parishioners.

Belonging to Vicariate of Our Lady of Grace is like being a part of a big family it is an enviable instrument for further growth and development. The unified sharing and interactions enriched the lay members and encourage them to work harder in the apostolic vineyard of God.